Bisultap 18% AS – Nereistoxin-Analog Insecticide for Rice Pest Management

Product Positioning: A low-toxicity, eco-friendly insecticide specifically engineered for integrated rice pest management, disrupting pest neural transmission via competitive nAChR inhibition. Ideal for sustainable agriculture and IPM systems.

1. Technical Specifications

Parameter	Specification
Active Ingredient	Bisultap 18% (w/w)
Chemical Class	Sulfur-containing alkaloid analog
Formulation	Aqueous Solution (AS)
Mode of Action	nAChR blocker → neuromuscular paralysis
Water Solubility	>500 g/L (20°C)
pH Range	4.5-6.5
Shelf Life	24 months (5-30°C storage)

2. Target Pests & Efficacy Data

Primary Control (Rice Ecosystems):

Rice stem borers (Chilo suppressalis, Scirpophaga incertulas)
Leaf folders (Cnaphalocrocis medinalis)
Brown planthopper (Nilaparvata lugens)

Efficacy Metrics (Field Trials):

Pest	Mortality (72 HAT)	Residual (7 DAT)
Yellow stem borer	92.3%	85.7%
Brown planthopper	88.1%	76.2%
Rice leaf folder	94.6%	89.4%

HAT = Hours After Treatment | DAT = Days After Treatment

3. Application Protocol

Crop	Pest	Dosage	Spray Volume	Critical Timing
Paddy rice	Stem borers	900-1200 mL/ha	300-400 L/ha	Egg mass hatching stage
Paddy rice	Planthoppers	750-1000 mL/ha	400-500 L/ha	Nymph emergence peak
Vegetables	Leaf miners	600-800 mL/ha	500-600 L/ha	First mine appearance

Operational Guidelines:

Apply via submerged root zone irrigation (rice) or foliar spray
Maintain 3-5 cm water layer in rice fields for 72 hours post-application
Avoid spraying when temperature >35°C or wind speed >15 km/h

4. Environmental & Safety Profile

Toxicology Data:

WHO Classification: U (Unlikely hazardous, acute oral LD50 >5000 mg/kg)
Honeybee Safety: Practically non-toxic (LD50 >100 μg/bee)
Fish Toxicity: LC50 (96h) = 12.8 mg/L (moderately toxic)

Precautionary Measures:
⚠️ Re-entry Interval: 12 hours
⚠️ Buffer Zones: 10m from aquatic habitats
⚠️ PHI: Rice = 21 days, Leafy vegetables = 14 days

5. Resistance Management

Rotation Partners (MoA Groups):

Neonicotinoids (Group 4A): Imidacloprid 17.8% SL
Pyrroles (Group 13): Chlorfenapyr 10% SC
IGRs (Group 16): Buprofezin 25% SC

Global Status:

Registered in China, Vietnam, India
Not approved in EU/US (MRL not established)

Packaging Options:

250 mL, 500 mL (AS bottles)
1 L, 5 L (HDPE jerrycans)
20 L (polyethylene drums)

Storage Requirements:

Protect from freezing (<5°C causes crystallization)
Agitate before use if stored >6 months

7. Performance Advantages

Parameter	Bisultap 18% AS	Conventional OP
Mammalian Toxicity	Extremely Low	High
Bee Safety	Excellent	Critical Risk
Resistance Development	Slow (30+ generations)	Rapid (5-8 gens)
Rainfastness	1 hour	6 hours