Propiconazole 250g/L EC Fungicide | Systemic Disease Control

Propiconazole 250g/L EC (Emulsifiable Concentrate) is a systemic triazole fungicide designed to control a broad spectrum of fungal diseases in cereals, fruits, vegetables, turf, and ornamentals. As an ergosterol biosynthesis inhibitor (EBI), it disrupts fungal cell membrane formation, providing preventive and curative activity against pathogens like rusts, powdery mildews, and leaf spots. The 250g/L EC formulation ensures high solubility and rapid plant uptake for efficient disease management.

Technical Specifications

Active Ingredient: Propiconazole (CAS No. 60207-90-1)
Molecular Formula: C₁₅H₁₇Cl₂N₃O₂
Mode of Action: Inhibits CYP51 (sterol 14α-demethylase), blocking ergosterol synthesis in fungal cell membranes.
Formulation: 250g/L EC (Emulsifiable Concentrate)
Physical State: Yellow to brown liquid
Solubility: 100 ppm in water; soluble in acetone, xylene
Vapor Pressure: 4.0×10⁻⁸ mmHg at 25°C
pH Range: 5.0–8.0 (stable in neutral to slightly acidic conditions)

Mode of Action

Systemic Uptake: Absorbed through leaves and roots, translocating via xylem to untreated tissues.
Target Disruption: Binds to CYP51 enzyme, preventing demethylation of lanosterol to ergosterol.
Cell Membrane Collapse: Weakened membranes lead to leakage of cellular contents and fungal death.
Symptom Control: Halts mycelial growth, spore production, and disease progression within 24–48 hours.

Application Guide

Crop	Target Diseases	Dosage (L/ha)	Timing
Wheat	Leaf rust, powdery mildew	0.5–1.0	Flag leaf emergence
Barley	Net blotch, scald	0.4–0.8	Tillering to stem elongation
Rice	Sheath blight, blast	0.6–1.2	Boot stage
Grapes	Powdery mildew, black rot	0.8–1.5	Pre-bloom to veraison
Turfgrass	Brown patch, dollar spot	0.3–0.6	At first sign of disease

Tips:

Water Volume: 200–400 L/ha for foliar sprays; ensure thorough coverage.
Adjuvants: Add non-ionic surfactant (0.25% v/v) to enhance leaf penetration.
Rainfastness: 4–6 hours post-application.
Mix Compatibility: Tank mix with mancozeb or chlorothalonil for broader spectrum control.

Key Advantages

Broad-Spectrum Control: Effective against 30+ pathogens, including rusts, mildews, and blights.
Systemic Protection: Moves throughout the plant, protecting new growth.
Residual Activity: 14–21 days of disease suppression, reducing application frequency.
Crop Safety: Selective in cereals, fruits, and turf when used at labeled rates.
Resistance Management: Rotate with strobilurins (e.g., azoxystrobin) or SDHIs (e.g., boscalid) to delay resistance.

Safety & Environment

Toxicity:
- Low mammalian toxicity (LD₅₀ > 2000 mg/kg); harmful if inhaled.
- Moderately toxic to fish (LC₅₀ 2–5 mg/L); avoid water runoff.
Environmental Fate:
- Soil half-life: 28–60 days (degrades via microbial activity).
- Low volatility; minimal risk of vapor drift.

Packaging

Standard: 1L, 5L, 20L COEX containers.
Custom: Private labeling available for distributors.

FAQ: Mixing Propiconazole 250g/L EC with Other Pesticides

1. Can Propiconazole 250g/L EC be mixed with insecticides?

Yes, in most cases. Propiconazole is commonly mixed with pyrethroids (e.g., deltamethrin), neonicotinoids (e.g., imidacloprid), or organophosphates (e.g., chlorpyrifos) for combined disease and pest control. Always check labels for specific compatibility statements.

2. Is it safe to mix Propiconazole with herbicides?

With caution. Avoid mixing with highly acidic herbicides (e.g., glyphosate in acidic formulations) or alkaline herbicides (e.g., 2,4-D salts), which may cause degradation or phytotoxicity. Test small batches before full application.

3. Can I mix Propiconazole with other fungicides?

Yes, and it’s often recommended for resistance management. Compatible fungicides include:

Chlorothalonil (protectant)
Azoxystrobin (strobilurin)
Mancozeb (dithiocarbamate)
Mixing systemic (propiconazole) and protectant fungicides broadens disease control.

4. What happens if I mix Propiconazole with an incompatible pesticide?

Incompatible mixes may cause:

Reduced efficacy (e.g., propiconazole degradation in alkaline conditions)
Physical separation (precipitation, oil layers)
Crop damage (phytotoxicity from formulation interactions)

5. How to test pesticide compatibility before mixing?

Add 100 ml water to a clear container.
Add each pesticide at labeled rates.
Stir and observe for 30 minutes. Avoid use if:
- Cloudiness, flakes, or oil droplets form.
- Excessive foaming or viscosity changes occur.

6. What is the correct order for mixing pesticides with Propiconazole EC?

Fill tank 1/3 with water.
Add water-soluble products (e.g., fertilizers).
Add wettable powders (WP).
Add suspensions (SC).
Add emulsifiable concentrates (EC, including propiconazole).
Add adjuvants last.
Fill remaining tank with water and agitate.

7. Can Propiconazole be mixed with foliar fertilizers?

Yes, with water-soluble fertilizers (e.g., N-P-K, micronutrients). Avoid high-concentration fertilizers, which may increase leaf burn risk. Test compatibility first.

8. Are there adjuvants that should not be mixed with Propiconazole?

Avoid mineral oils at high rates.
Check HLB (hydrophilic-lipophilic balance) of surfactants; incompatible HLB values may cause emulsion breakdown.
Non-registered adjuvants (e.g., homemade oils) are not recommended.

9. Does mixing Propiconazole with other pesticides affect its residual activity?

Generally no, if compatible. However, some protectant fungicides (e.g., mancozeb) may slightly reduce systemic movement of propiconazole. Follow label rates for optimal residual control (14–21 days).

10. Can I mix Propiconazole with biological pesticides (e.g., Bacillus thuringiensis)?

Proceed with caution. Chemical fungicides like propiconazole may reduce the efficacy of biological agents. If needed, apply biologicals separately or at least 7 days apart.

11. Does the pH of the mix affect Propiconazole stability?

Yes. Propiconazole is stable in pH 5–8. Alkaline mixes (pH >8) degrade the active ingredient, while highly acidic mixes (pH <5) may cause formulation instability. Test mix pH with litmus paper.

12. Are there crop-specific mixing restrictions?

Yes. For example:

On grapes, avoid mixing with certain sulfur-based fungicides.
On turf, ensure the mix does not enhance stress during hot weather.
Always consult crop-specific label guidelines.

13. Can tank mixes with Propiconazole be stored for later use?

No. Prepare only the amount needed for immediate application. Most mixes are unstable after 24 hours, and efficacy may decline.

14. What should I do if a tank mix causes phytotoxicity?

Stop application immediately.
Rinse crops with clean water to remove excess residue.
Contact a local agronomist or extension service for damage assessment.

15. Does mixing Propiconazole with other triazoles increase resistance risk?

Yes. Avoid mixing triazoles (e.g., propiconazole + tebuconazole), as they share the same mode of action. Rotate with different classes (e.g., strobilurins) to manage resistance.

16. Are there regional regulations on Propiconazole tank mixes?

Yes. For example:

In the EU, mixes must comply with MRL regulations.
In the U.S., some state agencies require pre-approval for certain combinations.
Consult local agricultural authorities for compliance.

17. Can I mix Propiconazole with a surfactant to improve coverage?

Yes, but use a non-ionic surfactant at 0.25% v/v (as labeled). Excessive surfactant may increase leaf burn risk, especially on sensitive crops (e.g., young seedlings).

18. What’s the risk of mixing Propiconazole with copper-based fungicides?

Copper formulations are often alkaline, which can degrade propiconazole. Avoid mixing; if necessary, apply copper and propiconazole 7–10 days apart.

19. Does mixing affect the pre-harvest interval (PHI)?

Yes. The PHI is determined by the longest PHI of any product in the mix. For example, if propiconazole has a 30-day PHI and an insecticide has a 14-day PHI, the mix’s PHI is 30 days.