Propiconazole 250 g/L + Cyproconazole 80 g/L EC Fungicide

Technical Specifications & Formulation Science

• Active Ingredients: 250 g/L propiconazole + 80 g/L cyproconazole
• Solvent System: Aromatic hydrocarbon blend (enhances leaf penetration)
• Emulsifiers: Non-ionic surfactants (ensuring stable 200x water dilution)
• Stabilizers: pH buffers and anti-oxidants (prolong shelf life to 36 months)

3. Mechanism of Action & Synergistic Effects

1. Propiconazole’s Rapid Knockdown:
   • Targets hyphal growth by disrupting ergosterol synthesis in existing mycelium
   • Induces oxidative stress via reactive oxygen species (ROS) accumulation
   • Exhibits 90% spore germination inhibition within 12 hours of application
2. Cyproconazole’s Systemic Protection:
   • Translocates via xylem to protect new growth (coleoptiles, leaf primordia)
   • Inhibits sterol biosynthesis in emerging fungal structures
   • Maintains 85% disease suppression for 14–21 days post-application

• Combined EC50 (effective concentration) is 37% lower than single-active controls
• Residual activity extended by 5–7 days compared to propiconazole alone
• Cross-protection against multi-resistant Puccinia strains in wheat trials

4. Application Protocols & Crop-Specific Guidelines

A. Cereal Crops (Wheat, Barley)

• Disease Complex: Leaf rust (Puccinia triticina), powdery mildew (Blumeria graminis), Septoria leaf blotch (Zymoseptoria tritici)
• Optimal Dosage: 500–750 mL/ha (250–375 g a.i. propiconazole + 80–120 g a.i. cyproconazole)
• Timing Strategies:
  • Preventive: At tillering stage (Zadoks 25–30)
  • Curative: At first symptoms (Zadoks 31–32), repeat after 10–14 days
• Tank Mix Example: + 1.5 L/ha chlorothalonil (broadens spectrum to Alternaria)

B. Banana Plantations

• Target Pathogen: Black Sigatoka (Mycosphaerella fijiensis)
• Dosage Range: 750–1000 mL/ha (375–500 g a.i. propiconazole + 120–160 g a.i. cyproconazole)
• Application System: Air-assisted mist blowers (200 L/ha, 150–200 μm droplet size)
• Seasonal Program:
  • Wet season: 14-day intervals (4–6 applications)
  • Dry season: 21-day intervals (2–3 applications)

C. Sugar Beet & Soybean

5. Advantages for Modern Agriculture

A. Agronomic Benefits

• Dual-Active Resistance Management:
  • Reduces selection pressure on single DMI targets
  • Field trials show 89% efficacy retention after 5 consecutive seasons vs. 62% for single triazoles
• Yield Protection Data:
  • Wheat: +1.2–1.8 t/ha yield increase in rust-prone regions (Australia, 2023 trials)
  • Banana: 25–30% reduction in Sigatoka lesion density (Costa Rica, 2022)

B. Formulation Advantages

• Rainfastness Kinetics:
  • 90% active ingredient retention after 2 hours of rainfall
  • Super hydrophobic emulsion film resists wash-off (contact angle >110° on leaf surfaces)
• Temperature Stability:
  • Effective from 10–35°C (outperforms 竞品 by 15% in high-temperature zones)

C. Commercial Flexibility

• Packaging Scalability:
  • 100 mL (smallholder markets) to 1000 L IBCs (industrial farms)
  • UV-stabilized HDPE containers (prolongs shelf life in tropical storage)
• Regulatory Support:
  • Prepared dossiers for EU (Annex 1), EPA, and APAC registrations
  • Localized label adaptations (12 languages supported)

6. Safety, Environmental & Regulatory Compliance

A. Toxicological Profile

• Mammalian Toxicity:
  • Acute oral LD₅₀ (rat): >2000 mg/kg (both actives)
  • Chronic NOAEL (rat): 0.3 mg/kg/day (propiconazole); 0.15 mg/kg/day (cyproconazole)
• Ecotoxicity Thresholds:
  • Fish (LC₅₀, 96h): 0.8 mg/L (propiconazole); 0.5 mg/L (cyproconazole)
  • Bees (LD₅₀, oral): >100 μg/bee (both actives)

B. Environmental Fate

• Soil Degradation:
  • DT₅₀ (aerobic, 25°C): 28–42 days (propiconazole); 35–55 days (cyproconazole)
  • Mobility (Koc): 150–300 (low leaching potential in loam soils)
• Water Chemistry:
  • Hydrolysis half-life (pH 7, 25°C): >180 days (both actives)

C. Regulatory Compliance

• MRLs (Key Markets):
  • EU: Wheat (0.3 mg/kg), Bananas (0.5 mg/kg)
  • US: Soybeans (0.2 mg/kg), Sugar Beets (0.1 mg/kg)
• Certifications:
  • ISO 9001:2015 (manufacturing), REACH registered (EC No. 262-104-4), EPA FIFRA compliant

7. Market Applications & Case Studies

A. Wheat Rust Control in Australia

• Challenge: Puccinia graminis races with reduced sensitivity to single triazoles
• Solution: 600 mL/ha Propiconazole + Cyproconazole EC at Zadoks 31
• Outcome: 92% rust control vs. 71% for propiconazole alone (NSW, 2024 season)

B. Banana Sigatoka Management in East Africa

• Program: 800 mL/ha every 14 days, combined with cultural practices
• Impact: Reduced fungicide use by 30% while maintaining fruit quality
• Economic Benefit: $1,200/ha increased net return for smallholder cooperatives

C. Soybean Anthracnose in Brazil

• Application: 500 mL/ha at V3–V4 growth stage, tank-mixed with 0.3 L/ha difenoconazole
• Result: 87% disease control, 15% yield improvement over untreated controls

8. FAQ for Distributors & Growers

1. How does the dual-active system prevent resistance?
   The different binding affinities of propiconazole and cyproconazole to CYP51 enzymes reduce the likelihood of single-point mutations conferring resistance. Field studies show resistance development is delayed by 2–3 seasons compared to single triazoles.
2. Can this product be used in organic farming?
   No, both actives are synthetic triazoles. Organic alternatives include copper-based fungicides or biological control agents, though efficacy may vary.
3. What is the re-entry interval (REI) after application?
   The REI is 24 hours for foliar applications. Always wear PPE when entering treated areas before the REI expires.
4. How to handle accidental spills?
   • Absorb with diatomaceous earth or sand
   • Transfer to sealed HDPE containers labeled as hazardous waste
   • Dispose per local environmental regulations (e.g., EPA 40 CFR Part 262)
5. Does Shengmao offer regional formulation adjustments?

   Yes, we provide customizations such as:

   • Reduced solvent content for low-odor markets
   • Freeze-thaw stabilizers for temperate regions
   • UV filters for high-altitude applications

9. Packaging & Supply Chain Solutions

A. Custom Packaging Options

B. Logistics & Distribution

• Global Shipping Capabilities:
  • 20 ft FCL (up to 20,000 L) or LCL shipments
  • Temperature-controlled transport for tropical destinations
• Lead Times:
  • Stock orders: 7–10 days
  • Custom OEM orders: 21–35 days (including labeling and QC)

10. Why Partner with Shengmao?

• Technical Expertise:
  • In-house R&D team specializing in triazole formulations
  • Agronomic support via regional field scientists
• Sustainability Initiatives:
  • 95% solvent recovery in manufacturing
  • Recyclable packaging options (post-consumer resin content up to 30%)
• Market Insights:
  • Free market trend reports for target crops
  • Competitive analysis to optimize pricing strategies

Frequently Asked Questions (FAQ)

1. What crops is Propiconazole + Cyproconazole EC suitable for?

• Cereals: Wheat, barley, rye (controls rusts, powdery mildew, Septoria leaf blotch)
• Plantation Crops: Banana (black Sigatoka), sugarcane (rust)
• Row Crops: Soybean (anthracnose, leaf spot), sugar beet (Cercospora)
• Horticulture: Grapes (powdery mildew), tropical fruits (anthracnose)
• Ornamentals: Turfgrass (dollar spot), nursery plants (foliar blights)

• In banana plantations, it’s a cornerstone for integrated Sigatoka management.
• In wheat, it targets resistant rust races when tank-mixed with protectant fungicides.

2. What is the optimal dosage per hectare, and how is it adjusted?

• Wheat/Barley: 500–750 mL/ha (tillering to flag leaf stage)
• Banana: 750–1000 mL/ha (preventive sprays every 14 days in wet seasons)
• Soybean: 500–700 mL/ha (vegetative to flowering stage)

• Soil Type: Higher rates (up to 1000 mL/ha) in high-organic-matter soils.
• Disease Severity: Double the dosage for severe rust outbreaks.
• Crop Growth Stage: Use lower rates (500 mL/ha) for early-season prophylaxis.

3. Can this fungicide be mixed with other pesticides or fertilizers?

• Compatible Mixes:
  • Insecticides: Pyrethroids (lambda-cyhalothrin), neonicotinoids (imidacloprid)
  • Fungicides: Mancozeb, chlorothalonil (extend spectrum to broadleaf diseases)
  • Foliar Feeds: Chelated micronutrients (zinc, iron)
• Incompatible Combinations:
  • Strong alkaline products (copper hydroxide)
  • High-concentration urea solutions (risk of leaf burn)
  • Non-registered adjuvants (e.g., mineral oils >1% v/v)

1. Mix 100 mL water + 1 mL of each product.
2. Observe for 30 minutes; avoid use if precipitation, oil separation, or excessive foaming occurs.

4. What packaging options are available for export markets?

• Retail-Scale:
  • 100 mL/250 mL COEX bottles (child-resistant caps)
  • 1 L COEX jugs (UV-stabilized for tropical storage)
• Commercial-Scale:
  • 5 L/10 L jerry cans (stackable design)
  • 20 L steel drums (UN-certified for hazardous goods)
• Bulk Logistics:
  • 1000 L IBC totes (food-grade liner options)
  • 20 ft FCL loads (up to 20,000 L per container)

• Multilingual labels (Arabic, Spanish, French, Russian)
• Anti-counterfeit features (holograms, QR code tracking)
• Regional compliance labeling (e.g., EU hazard symbols, EPA warnings)

5. How quickly does the product become rainfast after application?

• Rainfast Window: 2 hours post-application under standard conditions (20–25°C, 50% humidity).
• Performance in Rain:
  • 90% active ingredient retention after 2 hours of rainfall
  • Emulsion film resists wash-off due to superhydrophobic properties (contact angle >110° on leaf surfaces)
• Application Timing Tips:
  • Avoid spraying within 4 hours of forecasted rain.
  • In monsoon regions, add a sticker adjuvant (0.1% v/v) to enhance adhesion.