Tebuconazole 50% + Trifloxystrobin 25% WDG: Synergistic Fungicide for Broad – Spectrum Disease Control

2. Chemical Properties & Formulation

3. Mode of Action & Synergy

3.1 Tebuconazole’s Mechanism

• Disrupts fungal cell membrane integrity by inhibiting lanosterol 14α – demethylase, a key enzyme in ergosterol synthesis.
• Systemic translocation through xylem, providing curative control of existing infections.

3.2 Trifloxystrobin’s Mechanism

• Inhibits cytochrome bc₁ complex in mitochondrial electron transport chain, blocking ATP production.
• Protects plants by preventing spore germination and mycelial growth.

3.3 Synergistic Benefits

• Broad – Spectrum Efficacy: Combines triazole’s curative power with strobilurin’s protective activity.
• Prolonged Residual: Tebuconazole’s 14 – 21 – day residual + Trifloxystrobin’s 7 – 10 – day protection = up to 28 – day disease control.
• Resistance Management: Different action sites reduce the risk of pathogen resistance development.

4. Target Crops & Diseases

5. Application Guide

5.1 Timing & Method

• Preventive Application: Apply at crop growth stages prone to disease (e.g., wheat tillering, grape flowering).
• Curative Application: Use within 3 – 5 days of initial disease symptoms for optimal control.
• Spray Technique: Dilute 150 – 300 g of WDG in 300 – 500 L water/ha, applying evenly to both leaf surfaces.

5.2 Compatibility

• Tank Mixes: Compatible with most insecticides and foliar fertilizers; avoid mixing with strong alkalis.
• Adjuvants: Add non – ionic surfactants (0.2% v/v) to improve leaf adhesion in dry conditions.

6. Key Features & Benefits

1. Dual – Mode Systemic Action
   • Tebuconazole: Translocates acropetally to new growth
   • Trifloxystrobin: Penetrates leaf cuticles for translaminar protection
2. Crop Health Enhancement
   • Promotes chlorophyll synthesis, leading to greener foliage and improved photosynthesis.
   • Strengthens plant cell walls, reducing stress from abiotic factors (drought, heat).
3. Residue & Regulatory Compliance
   • Short soil half – life (7 – 14 days for tebuconazole; 5 – 10 days for trifloxystrobin).
   • Meets MRL standards in major markets (e.g., EU: 0.1 – 0.5 mg/kg for cereals).

7. Safety & Environmental Precautions

• Toxicity:
  • Low acute toxicity (LD₅₀ > 2000 mg/kg for both ingredients).
  • Moderate toxicity to fish (LC₅₀ 0.1 – 1 mg/L); maintain 30 m buffer from water bodies.
• Personal Protection:
  • Wear chemical – resistant gloves, goggles, and coveralls during mixing and application.
  • Avoid spraying in windy conditions to prevent drift onto sensitive crops.

8. Packaging & Storage

• Packaging: 1 kg, 5 kg, 25 kg HDPE bags with moisture – proof liners.
• Shelf Life: 3 years when stored at 5 – 30°C in a cool, dry place away from direct sunlight.

9. Field Efficacy Data

• Wheat Trials in Europe:
  200 g/ha reduced septoria leaf blotch by 92% and increased grain yield by 15% compared to untreated plots.
• Grapevine Trials in California:
  150 g/ha controlled powdery mildew with 95% efficacy, improving grape sugar content by 2 – 3 Brix.

10. Resistance Management Tips

1. Rotation Strategy:
   • Alternate with fungicides from different chemical classes (e.g., dithiocarbamates, phenylamides).
2. Dose Adherence:
   • Avoid under – dosing, which can select for resistant pathogen strains.
3. Monitoring:
   • Scout fields regularly to detect early signs of resistance (e.g., reduced control efficacy).